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Phospho-LRP6 (Ser1490) Recombinant Antibody, AbBy Fluor-488 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-62889r-bf488-100ul
Product Name Phospho-LRP6 (Ser1490) Recombinant Antibody, AbBy Fluor-488 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation AbBy Fluor-488
Host Rabbit
Source KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490
Modification Site Ser1490
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4040
Swiss Prot O75581
Subcellular location Cytoplasm, Cell membrane
Synonyms Low-density lipoprotein receptor-related protein 7.
Background Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Application Dilution
WB 1:300-5000