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TRAP1/HSP75 Recombinant Antibody

Applications

  • WB
  • IP

Reactivity

  • Human
Overview
Catalog # bsm-62997r
Product Name TRAP1/HSP75 Recombinant Antibody
Applications
WB IP
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Hsp75
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 10131
Swiss Prot Q12931
Subcellular location Cytoplasm
Synonyms HSP75; HSP 75; HSP90L; TRAP-1.
Background Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Application Dilution
WB 1:300-5000
IP 1-2ug

Frequently asked questions

Which applications is TRAP1/HSP75 Recombinant Antibody (bsm-62997R) validated for, and at what dilution?

bsm-62997R is validated for WB (1:300-5000); IP (1-2ug). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does TRAP1/HSP75 Recombinant Antibody (bsm-62997R) react with?

Tested reactivity: Human.

How should bsm-62997R be stored?

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

What immunogen was used to raise TRAP1/HSP75 Recombinant Antibody (bsm-62997R)?

KLH conjugated synthetic peptide derived from human Hsp75