c-FOS Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-70038M |
| Product Name | c-FOS Antibody |
| Applications |
WB
IHC
|
| Specificity | Specific for endogenous levels of the ~50 kDa c-FOS protein. |
| Reactivity | Human, Mouse, Rat, Bovine |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Recombinant full length human c-FOS expressed in and purified from E. Coli. |
| Clonality | Monoclonal |
| Clone # | 2H2 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | PBS + 50% glycerol and 5 mM NaN3 |
| Storage Condition | Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target | |
| Gene ID | 2353 |
| Swiss Prot | P01100 |
| Synonyms | Activator protein 1 antibody, AP 1 antibody, C FOS antibody, Cellular oncogene c fos antibody, Cellular oncogene fos antibody, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody, FBJ murine osteosarcoma viral oncogene homolog antibody, FBJ murine osteosarcoma viral v fos oncogene homolog antibody, FBJ Osteosarcoma Virus antibody, FOS antibody, FOS protein antibody, FOS_HUMAN antibody, G0 G1 switch regulatory protein 7 antibody, G0/G1 switch regulatory protein 7 antibody, G0S7 antibody, Oncogene FOS antibody, p55 antibody, proto oncogene c Fos antibody, Proto oncogene protein c fos antibody, Proto-oncogene c-Fos antibody, fos FBJ murine osteosarcoma viral oncogene homolog antibody |
| Background | c-FOS is a member of the FOS transcription factor family which forms dimers with c-JUN to produce the Activator Protein 1 (AP-1) complex which plays a key role in critical cellular processes such as cell proliferation, differentiation and apoptosis (Chiu et al., 1988). c-FOS expression has been demonstrated to be a useful marker of neuronal activation as it is rapidly induced following various stimuli (Hoffman et al., 1993). Additionally, c-FOS has been shown to be overexpressed in a variety of malignant tumor types (Milde-Langosch 2005). |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | |