GluR1 Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-70120M |
| Product Name | GluR1 Antibody |
| Applications |
WB
|
| Specificity | Specific for endogenous levels of the ~105 kDa GluR1 protein. |
| Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GluR1, conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Monoclonal |
| Clone # | RH95 |
| Isotype | IgG2a |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage Condition | Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target | |
| Gene ID | 50592 |
| Swiss Prot | P19490 |
| Synonyms | GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, THUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody |
| Background | The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is GluR1 Antibody (bsm-70120M) validated for, and at what dilution?
bsm-70120M is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GluR1 Antibody (bsm-70120M) react with?
Tested reactivity: Mouse, Rat.
How should bsm-70120M be stored?
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. Storage buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
What immunogen was used to raise GluR1 Antibody (bsm-70120M)?
Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GluR1, conjugated to keyhole limpet hemocyanin (KLH).