Neurofilament NF-L Antibody

Applications

Reactivity

Human
Mouse
Rat
Bovine
Chicken

Overview
Catalog #	bsm-70171m
Product Name	Neurofilament NF-L Antibody
Applications	WB, IHC
Specificity	Specific for endogenous levels of the ~68 kDa Neurofilament L protein.
Reactivity	Human, Mouse, Rat, Bovine, Chicken
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Preparation of porcine NF-L.
Clonality	Monoclonal
Clone #	#REF!
Isotype	IgG1
Concentration	2 mg/ml
Purification	Purified by Protein G.
Storage Buffer	PBS + 10 mM NaN3.
Storage Condition	Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20 C or -80 C, while keeping a working aliquot stored at 4 C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Target
Gene ID	4747
Swiss Prot	P02547
Synonyms	68 kDa neurofilament protein antibody, 68kDa Neurofilament antibody, 68kDa neurofilament protein antibody, CMT1F antibody, CMT2E antibody, FLJ53642 antibody, Light molecular weight neurofilament protein antibody, NEFL antibody, Neurofilament light antibody, Neurofilament light polypeptide 68kDa antibody, Neurofilament light polypeptide antibody, Neurofilament protein, light chain antibody, Neurofilament subunit NF L antibody, Neurofilament triplet L protein antibody, NF-L antibody, NF68 antibody, NFL antibody, NFL_HUMAN antibody
Background	Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about ~68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2).
Application Dilution
WB
IHC