Neurofilament NF-M Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-70173m |
| Product Name | Neurofilament NF-M Antibody |
| Applications |
WB
IHC
|
| Specificity | Specific for endogenous levels of the ~145 kDa neurofilament M protein. |
| Reactivity | Human, Mouse, Rat, Bovine, Chicken |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Preparation containing the extreme C-terminus of rat NF-M, expressed in and purified from E. Coli. |
| Clonality | Monoclonal |
| Clone # | 3H11 |
| Isotype | IgG1 |
| Concentration | 2 mg/ml |
| Purification | Purified by Protein G. |
| Storage Buffer | PBS + 10 mM NaN3. |
| Storage Condition | Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy |
| Target | |
| Gene ID | 24588 |
| Swiss Prot | P12839 |
| Synonyms | 150 kDa Neurofilament Medium antibody, 160 kDa neurofilament protein antibody, Medium polypeptide 150kDa antibody, NEF3 antibody, Neurofilament 3 antibody, Neurofilament 3 medium antibody, Neurofilament medium polypeptide antibody, Neurofilament protein M antibody, Neurofilament triplet M protein antibody, Neurofilament-3 (150 kD medium) antibody, NF-M antibody, NFM antibody |
| Background | Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). |
| Application Dilution | |
| WB | |
| IHC | |