D-Dimer Mouse Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | v1104-1mg |
| Product Name | D-Dimer Mouse Monoclonal Antibody |
| Applications |
ELISA
LFA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 3C12 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | affinity purified by Protein A |
| Storage Buffer | potassium phosphate buffer and sodium chloride. No preservatives are added. |
| Storage Condition | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 2243 |
| Synonyms | D DIMER; D-DIMER |
| Background | Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| LFA | N/A |
Frequently asked questions
Which applications is D-Dimer Mouse Monoclonal Antibody (V1104) validated for, and at what dilution?
V1104 is validated for ELISA (1:500-1000); LFA(N/A). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does D-Dimer Mouse Monoclonal Antibody (V1104) react with?
Tested reactivity: Human.
How should V1104 be stored?
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: potassium phosphate buffer and sodium chloride. No preservatives are added.