Human NT-proBNP Mouse Monoclonal Antibody

Overview
Catalog #	v3307-1mg
Product Name	Human NT-proBNP Mouse Monoclonal Antibody
Applications	ELISA, LFA
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Clonality	Monoclonal
Clone #	5A1
Isotype	IgG1
Concentration	Lot Dependent
Purification	affinity purified by Protein A
Storage Buffer	0.01M PBS (pH7.4).
Storage Condition	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	4879
Synonyms	Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP.
Background	Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Application Dilution
ELISA	1:500-1000
LFA	N/A