Human BNP Goat pAb

Overview
Catalog #	v3322-1mg
Product Name	Human BNP Goat pAb
Applications	ELISA, LFA
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Goat
Clonality	Polyclonal
Isotype	IgG1
Concentration	Lot Dependent
Purification	affinity Purified by Protein G.
Storage Buffer	0.01M PBS(pH7.4).
Storage Condition	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	4879
Synonyms	Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP.
Background	Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Application Dilution
ELISA	1:500-1000
LFA	N/A