PGII Mouse Monoclonal Antibody

Overview
Catalog #	v4205-1mg
Product Name	PGII Mouse Monoclonal Antibody
Applications	ELISA, LFA
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Clonality	Monoclonal
Clone #	7D5
Isotype	IgG1
Concentration	Lot Dependent
Purification	affinity purified by Protein A
Storage Buffer	PBS (pH7.4).
Storage Condition	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	5225
Synonyms	PEPC_HUMAN; Gastricsin; EC:3.4.23.3; Pepsinogen C; PEPC; PGC; progastricsin;
Background	This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].
Application Dilution
ELISA	1:500-1000
LFA	N/A