phospho-Tau (Thr181) Mouse Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | v5226-1mg |
| Product Name | phospho-Tau (Thr181) Mouse Monoclonal Antibody |
| Applications |
ELISA
LFA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 10F4 |
| Isotype | IgG2b |
| Concentration | Lot Dependent |
| Purification | affinity purified by Protein A |
| Storage Buffer | 0.01M PBS (pH7.4). |
| Storage Condition | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 4137 |
| Synonyms | Tau (phospho T181); p-Tau (phospho T181); Tau(Phospho-Thr181); MAPT(phospho T181); p-Tau(Thr181); MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN. |
| Background | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| LFA | N/A |
Frequently asked questions
Which applications is phospho-Tau (Thr181) Mouse Monoclonal Antibody (V5226) validated for, and at what dilution?
V5226 is validated for ELISA (1:500-1000); LFA(N/A). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does phospho-Tau (Thr181) Mouse Monoclonal Antibody (V5226) react with?
Tested reactivity: Human.
How should V5226 be stored?
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M PBS (pH7.4).