| Overview |
| v7704-1mg |
| Human Serpin B3 Mouse Monoclonal Antibody |
| ELISA, LFA |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| Monoclonal |
| 2H6 |
| IgG2b |
| Lot Dependent |
| affinity purified by Protein A |
| PBS (pH7.4). |
| Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 6317 |
| HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A. |
| Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. |
| Application Dilution |
| ELISA |
1:500-1000 |
| LFA |
N/A |