Human Serpin B3 Mouse Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | v7706-1mg |
| Product Name | Human Serpin B3 Mouse Monoclonal Antibody |
| Applications |
ELISA
LFA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 9C11 |
| Isotype | IgG2a |
| Concentration | Lot Dependent |
| Purification | affinity purified by Protein A |
| Storage Buffer | PBS (pH7.4). |
| Storage Condition | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 6317 |
| Synonyms | HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A. |
| Background | Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| LFA | N/A |