Human CD40L Mouse Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | v7901-1mg |
| Product Name | Human CD40L Mouse Monoclonal Antibody |
| Applications | ELISA, LFA |
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 10A4 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | affinity purified by Protein A |
| Storage Buffer | 0.01M PBS(pH7.4) |
| Storage Condition | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 959 |
| Synonyms | TNFSF5; CD 154; CD 40L; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor(ligand) superfamily member 5; CD40L_HUMAN. |
| Background | CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| LFA | N/A |
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