Angiotensin I/BSA
Applications
| Overview | |
| Catalog # | y-0273b-1mg |
| Product Name | Angiotensin I/BSA |
| Applications |
OTHERS
|
| Specifications | |
| Conjugation | Unconjugated |
| Source | small molecule-conjugated carrier protein |
| Storage Buffer | 0.01M PBS(pH7.4) |
| Storage Condition | Store at -70°C or -20°C. Avoid repeated freeze/thaw cycles. |
| Target | |
| Background | Angiotensin I appears to have no biological activity and exists solely as a precursor to angiotensin 2. Angiotensin I is formed by the action of renin on angiotensinogen. Renin cleaves the peptide bond between the leucine (Leu) and valine (Val) residues on angiotensinogen, creating the ten-amino acid peptide (des-Asp) angiotensin I. Renin is produced in the kidneys in response to renal sympathetic activity, decreased intrarenal blood pressure at the juxtaglomerular cells, or decreased delivery of Na+ and Cl- to the macula densa. If less Na+ is sensed by the macula densa, renin release by juxtaglomerular cells is increased. |