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Recombinant mAbs vs. Polyclonals: How do You Choose?

Recombinant mAbs vs. Polyclonals: How do You Choose?

Antibodies are research powerhouses, but batch-to-batch variability can derail experiments. Recombinant monoclonal antibodies (mAbs) are often touted as the
consistency champions. But are they always the best choice? Let's cut through the noise.

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Are Recombinant Monoclonal Antibodies the Ultimate Solution for Batch-to-Batch Consistency in Research?

Are Recombinant Monoclonal Antibodies the Ultimate Solution for Batch-to-Batch Consistency in Research?

Recombinant monoclonal antibodies bring genetic precision, engineering flexibility, and cutting-edge quality control to the lab—dramatically reducing lot-to-lot differences that undermine reproducibility. In this deep dive, we unpack their advantages, explore remaining challenges around glycosylation and cost, and look ahead to AI-driven design and hybrid antibody strategies.

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