ZNRF3 Polyclonal Antibody, APC-Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9141R-APC-Cy7-100uL |
| Product Name | ZNRF3 Polyclonal Antibody, APC-Cy7 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | APC-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ZNRF3 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 84133 |
| Swiss Prot | Q9ULT6 |
| Subcellular location | Extracellular |
| Synonyms | RNF203; BK747E2.3; E3 ubiquitin-protein ligase ZNRF3; RING finger protein 203; Zinc/RING finger protein 3; ZNRF3; KIAA1133 |
| Background | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
| Application Dilution | |
| WB | IFIHC-P1:50-200 |
Frequently asked questions
Which applications is ZNRF3 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9141R-APC-Cy7) validated for, and at what dilution?
bs-9141R-APC-Cy7 is validated for IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ZNRF3 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9141R-APC-Cy7) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-9141R-APC-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ZNRF3 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9141R-APC-Cy7)?
KLH conjugated synthetic peptide derived from human ZNRF3
What are the excitation and emission wavelengths of the APC-Cy7 conjugate (bs-9141R-APC-Cy7)?
APC-Cy7 on bs-9141R-APC-Cy7: excitation / emission 650nm/780nm.