ZNRF3 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9141R-Biotin-100uL |
| Product Name | ZNRF3 Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
IHC-P
IHC-F
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ZNRF3 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 84133 |
| Swiss Prot | Q9ULT6 |
| Subcellular location | Extracellular |
| Synonyms | RNF203; BK747E2.3; E3 ubiquitin-protein ligase ZNRF3; RING finger protein 203; Zinc/RING finger protein 3; ZNRF3; KIAA1133 |
| Background | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
| Application Dilution | |
| WB | IHC-P1:200-400 |
| IHC-P | |
| IHC-F | |
Frequently asked questions
Which applications is ZNRF3 Polyclonal Antibody, Biotin Conjugated (bs-9141R-Biotin) validated for, and at what dilution?
bs-9141R-Biotin is validated for IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ZNRF3 Polyclonal Antibody, Biotin Conjugated (bs-9141R-Biotin) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-9141R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ZNRF3 Polyclonal Antibody, Biotin Conjugated (bs-9141R-Biotin)?
KLH conjugated synthetic peptide derived from human ZNRF3