Epitope Tag Antibodies

An epitope tag is a biological structure or sequence, recognized by an antibody, such as a protein or carbohydrate, that acts as an antigen. When no antibody is available for the protein/ molecule of interest, epitope tagging is a great alternative to allow researchers to track protein expression and localization.

The tag can be attached to a protein/molecule of interest by using chemical conjugation or genetic fusion. The tags can also improve solubility, folding, purification, and expression levels. With epitope tagging, affinity purification can be performed for the tagged molecule by using tag-specific antibodies coupled to chromatographic resins.