Glycitein

Overview
Catalog #	bs-76365c-10mg
Product Name	Glycitein
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 40957-83-3 Molecular formula: C16H12O5 Molecular weight: 284.26 Purity: >98% (HPLC) Appearance: White powder. Solubility: Sparingly soluble in water, DMSO or DMF (all <1mg/ml). InChiKey: DXYUAIFZCFRPTH-UHFFFAOYSA-N SMILES: OC1=C(OC)C=C2C(OC=C(C3=CC=C(O)C=C3)C2=O)=C1 SMILES: COC1=C(O)C=C2OC=C(C(=O)C2=C1)C1=CC=C(O)C=C1
Description	Glycitein is an O-methylated isoflavone. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been shown to have antioxidant properties and to inhibit c-Jun N-terminal kinase. It also has been shown to inhibit glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression, or to induce reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-kappa pathway in human gastric cancer cells.