Naphthol AS-TR phosphate

Overview
Catalog #	bs-76601c-1g
Product Name	Naphthol AS-TR phosphate
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 6 months after receipt when stored at -20°C.
Target
Product Information	CAS Number: 2616-72-0 Molecular formula: C18H15CINO5P Molecular weight: 391.74 Purity: >99% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in DMF or TRIS-HCl buffer. InChiKey: SHTFMUPUBYXPCD-UHFFFAOYSA-N SMILES: O=C(NC1=C(C)C=C(Cl)C=C1)C2=CC3=CC=CC=C3C=C2OP(O)(O)=O SMILES: CC1=C(NC(=O)C2=CC3=CC=CC=C3C=C2OP(O)(O)=O)C=CC(Cl)=C1
Description	Naphthol AS-TR Phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-TR Phosphate is converted to naphthol AS-TR displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology applications. Naphthol AS-TR Phosphate is a cyclic-AMP response element-binding protein (CREB)-CREB binding protein (CBP) transcription factor complex inhibitor and a potential therapeutic agent for lung cancer.