N-Vanillylnonanamide

Overview
Catalog #	bs-76607c-10g
Product Name	N-Vanillylnonanamide
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 2444-46-4 Molecular formula: C17H27NO3 Molecular weight: 293.41 Purity: >97% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in DMSO (10mg/ml), DMF (10mg/ml), ethanol (30mg/ml) or methanol (100mg/ml). InChiKey: RGOVYLWUIBMPGK-UHFFFAOYSA-N SMILES: OC1=C(OC)C=C(CNC(CCCCCCCC)=O)C=C1 SMILES: CCCCCCCCC(=O)NCC1=CC(OC)=C(O)C=C1
Description	Nonivamide is a transient receptor potential vanilloid type 1 (TRPV1) agonist and an analog of capsaicin, with anti-inflammatory, antiobesity and antifouling properties. Nonivamide has anti-inflammatory potential by inhibiting LPS-induced activation of the MAPK pathway. Nonivamide enhanced hyperthermia-induced apoptosis via a mitochondrial-caspase dependent pathway, and might be useful as cancer treatment enhancer. Nonivamide has also shown to be effective antiobesity agent by reducing energy intake, enhancing energy metabolism, decreasing serum triacylglycerol content and inhibiting adipogenesis via activation of the transient receptor potential cation channel subfamily V member 1 (TRPV1). Formulations containing nonivamide have been used in pepper spray weaponry for riot control.