MK-571

Overview
Catalog #	bs-82025c-5mg
Product Name	MK-571
Specifications
Storage Buffer	Yellow solid
Storage Condition	RT
Target
Product Information	Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4)1 displaying inverse agonist activity2, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance protein 1 (MRP1) inhibitor.3
Description	CAS Number: 115104-28-4 Chemical Name: 5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid Molecular weight: 515.09 Formula: C26H27ClN2O3S2 Solubility: DMSO (50 mg/ml) Physical Properties: Yellow solid Purity: 95% by TLC [10% methanol in methylene chloride; Rf = 0.34] NMR conforms