MK-886
| Overview | |
| Catalog # | bs-82026c-5mg |
| Product Name | MK-886 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. Also inhibits PPARα (80% inhibition at 10 µM).3 |
| Description | CAS Number: 118414-82-7 Chemical Name: 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid Molecular weight: 472.08 Formula: C27H34ClNO2S Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: 98% by TLC [ 5% methanol in methylene chloride; Rf = 0.35] NMR conforms |