AZD1152-HQPA

Overview
Catalog #	bs-83026c-5mg
Product Name	AZD1152-HQPA
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	AZD1152-HQPA is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM; Aurora A Ki = 1,369 nM.2 It inhibits the growth of tumors in multiple cancer models.3-6 Excessive ROS generation7 and upregulated tumor suppressor miRNAs8 have been proposed as a novel mechanisms of cytotoxicity of AZD1152-HQPA.
Description	CAS Number: 722544-51-6 Chemical Name: 3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide Molecular weight: 507.56 Formula: C26H30FN7O3 Solubility: DMSO (15 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms)