Milbemectin

Overview
Catalog #	bs-83105c-5-mg
Product Name	Milbemectin
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	An allosteric agonist at the Drosophila RDL GABA receptor.1,2 Also acts as an agonist at glutamate-gated chloride channels in insects.3 Mutations (specifically a G326E substitution) in the glutamate-gated chloride channel 3 (GluCl3) in phytophagous mites abolishes agonist activity resulting in resistance.4 Commercially used as an acaricide.
Description	CAS Number: 1799297-76-9 Chemical Name: Milbemycin A3: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-milbemycin B Milbemycin A4: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B Molecular weight: 542.71 (A4) Formula: C32H46O7 (A4) Solubility: DMSO (20 mg/ml) Ethanol (40 mg/ml) Physical Properties: White solid Purity: >98% HPLC; Milbemectin is a mixture of Milbemycin A3 (~30%) and Milbemycin A4 (~70%) NMR (Conforms)