Biotin-isoxazole
Applications
| Overview | |
| Catalog # | bs-83117c-1-mg |
| Product Name | Biotin-isoxazole |
| Applications | Life Science |
| Specifications | |
| Conjugation | Unconjugated |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Background | Exposure of cell or tissue lysates to biotin-isoxazole precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.1,2 In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones.3 SR domains were found to be the determinant that facilitates B-Isox precipitation.4 Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.5 |
| Application Dilution | |
| Life Science | N/A |
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