CID1067700

Overview
Catalog #	bs-83118c-5-mg
Product Name	CID1067700
Specifications
Storage Buffer	beige solid
Storage Condition	-20°C
Target
Product Information	A specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of b-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
Description	CAS Number: 314042-01-8 Chemical Name: 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid Molecular weight: 390.48 Formula: C18H18N2O4S2 Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms)