Obeticholic acid
| Overview | |
| Catalog # | bs-83338c-50mg |
| Product Name | Obeticholic acid |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo. |
| Description | CAS Number: 459789-99-2 Chemical Name: FXR agonist Molecular Weight: 420.63 Formula: C26H44O4 Solubility: DMSO (35 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms) |
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