PCI-34051
| Overview | |
| Catalog # | bs-83357c-25mg |
| Product Name | PCI-34051 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6 |
| Description | CAS Number: 950762-95-5 Chemical Name: HDAC8 inhibitor Molecular Weight: 296.33 Formula: C17H16N2O3 Solubility: DMSO (50 mg/ml) Physical Properties: Off-white solid Purity: >98% by TLC NMR (Conforms) |
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