Gimeracil

Overview
Catalog #	bs-83402c-100mg
Product Name	Gimeracil
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Gimeracil is a dihydropyrimidine dehydrogenase (DPD) inhibitor. DPD is involved in the degradation of pyrimidine-based chemotherapeutic drugs such as 5-fluorouracil (5-FU). Gimeracil is used along with 5-FU or Tegafur to prolong circulating concentrations of the drugs.1,2 Gimeracil has also been shown to act as a radiosensitizer via inhibition of homologous recombination in the repair of DNA double strand breaks.3
Description	CAS Number: 103766-25-2 Chemical Name: Dihydropyrimidine dehydrogenase inhibitor Molecular Weight: 145.54 Formula: C5H4ClNO2 Solubility: DMSO (5 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)