Repaglinide

Overview
Catalog #	bs-83406c-100mg
Product Name	Repaglinide
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Repaglinide is a blocker of the ATP-sensitive potassium channel Kir6 with hypoglycemic activity.1 Clinically useful antidiabetic agent. It displays 30-fold selectivity for pancreatic Kir6.2/SUR1 over cardiac Kir6.1/SUR2B and Kir6/SUR2A channels.2 Repaglinide displayed neuroprotective effects in Huntington disease3, Parkinson’s disease4, and ALS5 via blockade of the DREAM-ATF6 interaction.
Description	CAS Number: 135062-02-1 Chemical Name: Kir6 blocker Molecular Weight: 453.6 Formula: C27H36N2O4 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: >98% by TLC (NMR Conforms)