UK-5099

Overview
Catalog #	bs-83410c-25mg
Product Name	UK-5099
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Potent inhibitor of the mitochondrial pyruvate carrier (MPC).1 Rapidly increases glucose uptake in human monocytes.2 Attenuates mitochondrial oxidative phosphorylation and increases glycolysis creating greater stem-like properties in LnCap prostate cancer cells.3 Blocks the neuroprotective action of L-lactate or pyruvate during glutamate-induced excitotoxicity.4 Inhibits pyruvate transport across the plasma membrane of trypanosomes (Ki=49 μM).5
Description	CAS Number: 56396-35-1 Chemical Name: Mitochondrial pyruvate transporter inhibitor Molecular Weight: 288.30 Formula: C18H12N2O2 Solubility: DMSO (30 mg/ml) Ethanol (8 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC NMR (Conforms)