AS1842856

Overview
Catalog #	bs-83437c-25mg
Product Name	AS1842856
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	AS1842856 potent and selective FOXO1 inhibitor, IC50s=33 nM and >1 mM for FOXO3a and 4.1 Oral administration to diabetic db/db mice leads to a reduction of fasting plasma glucose levels.1 Suppresses autophagy, FSP27 expression and adipocyte differentiation.2 AS1842856 is a highly useful tool for probing the involvement of FOXO1 in cellular processes.3-5
Description	CAS Number: 836620-48-5 Chemical Name: FOXO1 inhibitor Molecular Weight: 347.39 Formula: C18H22FN3O3 Solubility: DMSO (10 mg/ml, warm) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms)