Calphostin C

Overview
Catalog #	bs-83449c-500ug
Product Name	Calphostin C
Specifications
Storage Buffer	Dark red to light brown solid
Storage Condition	-20°C
Target
Product Information	Potent and specific inhibitor of protein kinase C (PKC, IC50 = 50 nM).1 Inhibition of PKC is light dependent2 and is competitive with the diacylglycerol / phorbol ester binding site1. Calphostin C competes with the diacylglycerol / phorbol ester binding site in other proteins such as Munc13-1.3 Reverses oxycodone-induced tolerance to respiratory depression.4
Description	CAS Number: 121263-19-2 Chemical Name: Protein Kinase C inhibitor Molecular Weight: 790.77 Formula: C44H38O14 Solubility: DMSO (10 mg/ml) Physical Properties: Dark red to light brown solid Purity: 98% by HPLC NMR (Conforms)