STF-118804

Overview
Catalog #	bs-83451c-25mg
Product Name	STF-118804
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent and selective next generation inhibitor of nicotinamide phosphoribosyl transferase (NAMPT), inhibiting NAD+ biosynthesis from nicotinamide.1 It reduced the viability of most B-ALL cells with high potency (low nM range), eliminates leukemia stem cells from mouse bone marrow, and induces regression of ALL xenografts.1 It induces apoptosis and reduced neuroblastoma stem cell neurosphere formation in high-risk neuroblastoma cell lines.2 STF-118804 reduces the growth of pancreatic ductal adenocarcinoma cells.3
Description	CAS Number: 894187-61-2 Chemical Name: NAMPT inhibitor Molecular Weight: 461.54 Formula: C25H23N3O4S Solubility: DMSO (47 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms)