GW3965 HCl

Overview
Catalog #	bs-83713c-5mg
Product Name	GW3965 HCl
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	GW3965 is a potent and selective LXR agonist, activating human LXRα and β in cell-based reporter gene assays (EC50=190 and 30 nM respectively).1 Since LXR is a master regulator of cholesterol and fatty acid metabolism, GW3965 exerts a variety of effects including antiatherosclerotic2, antiinflammatory3 as well as antinociceptive4 and alteration of fat tissue distribution5. Orally active.
Description	CAS Number: 405911-17-3 Chemical Name: 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic acid, hydrochloride Molecular Weight: 618.52 Formula: C33H31ClF3NO3 • HCl Solubility: DMSO (48 mg/ml) Physical Properties: White solid Purity: >98% by HPLC (NMR Conforms)