Thiothixene

Overview
Catalog #	bs-83745c-5mg
Product Name	Thiothixene
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Thiothixene is a clinically useful typical antipsychotic.1 It acts as an antagonist at multiple receptors including dopamine D2 and D3 (sub-nanomolar), histamine H1, serotonin 5-HT7, and α1/2-adrenergic. Thiothixene stimulates efferocytosis, the phagocytic removal of apoptotic cells by macrophages, via increased expression of the retinol-binding protein receptor Stra6L leading to arginase 1 production.2 A potential new use for an old drug to facilitate the removal of diseased tissue.
Description	CAS Number: 3313-26-6 Chemical Name: ((Z)-N,N-Dimethyl-9-[3-(4-methyl-1-iperazinyl)propylidene]thioxanthene-2-sulfonamide Molecular Weight: 443.62 Formula: C23H29N3O2S2 Solubility: DMSO (20 mg/ml) with warming Physical Properties: White solid Purity: >98% by HPLC, NMR (Conforms)