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TJ-M2010-5

Overview
Catalog # bs-83819c-5mg
Product Name TJ-M2010-5
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6
Description CAS Number: 1357471-57-8

Chemical Name: 3-(4-Benzylpiperazin-1-yl)-N-(4-phenyl-1,3-thiazol-2-yl)propanamide

Molecular Weight: 406.55

Formula: C23H26N4OS

Solubility: DMSO (>25 mg/ml)

Physical Properties: White solid

Purity: >98% by HPLC NMR (Conforms)