| Overview |
| bs-51000R |
| RbAp 46/48 Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastoma-binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46 |
| Monoclonal |
| 6D1 |
| IgG2b |
| Not Determined |
| Ascites fluid from mouse containing 0.05% azide |
| Ascites fluid with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 5928 |
| Q09028 |
| Histone-binding protein RBBP4, RBBP4, p48, RBBP-4, RBAP48 |
| Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
| Application Dilution |
| WB |
1:300-5000 |
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