DKK2 Monoclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-51690m |
| Product Name | DKK2 Monoclonal Antibody |
| Applications | WB |
| Reactivity | Human |
| Predicted Reactivity | Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Recombinant human DKK2. |
| Clonality | Monoclonal |
| Clone # | #REF! |
| Concentration | 0.5ug/ul |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 27123 |
| Swiss Prot | Q9UBU2 |
| Subcellular location | Secreted |
| Synonyms | Dickkopf 2; Dickkopf gene 2; Dickkopf homolog 2; Dickkopf related protein 2; Dickkopf-2; Dickkopf-related protein 2; Dickkopf2; DKK 2; Dkk-2; DKK2_HUMAN; hDkk 2; hDkk-2; hDkk2. |
| Background | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
| Application Dilution | |
| WB | =1:500-1000 |
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