Overview |
bsm-52381R |
Apaf-1 (4G2) Monoclonal Antibody |
WB, IHC-P, IF(ICC), IHC |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Recombinant human Apaf-1 between 1 to 300 amino acids |
Monoclonal |
4G2 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
317 |
O14727 |
Apoptotic protease-activating factor 1, APAF-1, APAF1 |
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |
IHC |
|