Overview |
bsm-52389R |
N Cadherin (5G1) Monoclonal Antibody |
WB, FCM, IHC-P, IF(ICC), IHC |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant human N Cadherin between 150 to 250 amino acids |
Monoclonal |
5G1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
1000 |
P19022 |
Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, N-cadherin, CDH2 |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |
IHC |
|