Recombinant mouse ACOX1 protein, C-His

Overview
Catalog #	bs-42132p-100ug
Product Name	Recombinant mouse ACOX1 protein, C-His
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant mouse ACOX1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 386-661/661
Storage Buffer	20mM Tris-HCl (pH8.0)with 8M Urea.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	11430
Swiss Prot	Q9R0H0
Background	Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning.