| Overview |
| bs-42154p-100ug |
| Recombinant mouse IL18 protein, N-His |
| Others |
| Others |
| Specifications |
| Unconjugated |
| Recombinant mouse IL18 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 36-192/192 |
| 20mM Tris-HCl (pH8.0) with 2M Urea. |
| The product should be stored at -70°C or -20°C. |
| Target |
| 16173 |
| P70380 |
| IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |
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