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Recombinant human IL-18 protein

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42309P-100ug
Product Name Recombinant human IL-18 protein
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human IL-18 protein is expressed in E.coli. It contains the amino acid sequence of 37-193/193
Storage Buffer 20mM Tris-HCl (pH8.0) with 2M Urea.
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 29197
Swiss Prot P97636
Background IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.