Recombinant Human ACE2 Protein

$Recombinant Human ACE-2 protein on Tris-Bis PAGE\r\nunder reduced condition. The purity is greater than 90%.$

Overview
Catalog #	bs-46110P
Product Name	Recombinant Human ACE2 Protein
Applications	WB, ELISA
Reactivity	Human
Specifications
Conjugation	Unconjugated
Source	Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-His Tag
Storage Buffer	Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	NP_001358344.1
Swiss Prot	Q9BYF1
Background	Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don‚Äôt inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function.