C-176
| Overview | |
| Catalog # | bs-82806c-10mg |
| Product Name | C-176 |
| Specifications | |
| Storage Buffer | Brown or yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation. |
| Description | CAS Number: 314054-00-7 Chemical Name: N-(4-Iodophenyl)-5-nitrofuran-2-carboxamide Molecular weight: 358.09 Formula: C11H7IN2O4 Solubility: DMSO (25 mg/ml) Physical Properties: Brown or yellow solid Purity: 98% |
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