H-151
| Overview | |
| Catalog # | bs-82808c-10mg |
| Product Name | H-151 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice. |
| Description | CAS Number: 941987-60-6 Chemical Name: N-(4-Ethylphenyl)-N’-1H-indol-3-yl urea Molecular weight: 279.34 Formula: C17H17N3O Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: 98%, NMR (Conforms) |
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