MAFK (8C5) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51274M |
| Product Name | MAFK (8C5) Monoclonal Antibody |
| Applications |
WB
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK. |
| Clonality | Monoclonal |
| Clone # | 8C5 |
| Isotype | IgG1 |
| Concentration | 0.5ug/ul |
| Purification | Purified by Protein G. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 7975 |
| Swiss Prot | O60675 |
| Synonyms | P18; NFE2U; Transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit; MAFK |
| Background | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |